Search on: APC7 SUBUNIT, ANAPHASE-PROMOTING COMPLEX-CYCLOSOME 
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Descriptor English:   Apc7 Subunit, Anaphase-Promoting Complex-Cyclosome 
Descriptor Spanish:   Subunidad Apc7 del Ciclosoma-Complejo Promotor de la Anafase 
Descriptor Portuguese:   Subunidade Apc7 do Ciclossomo-Complexo Promotor de Anáfase 
Tree Number:   D08.811.464.938.750.092.992
D12.776.167.024.992
Definition English:   A highly conserved subunit of the anaphase-promoting complex (APC-C) containing multiple 34 amino acid tetratricopeptide repeats. These domains, also found in Apc3, Apc6, and Apc8, have been shown to mediate protein-protein interactions, suggesting that Apc7 may assist in coordinating the juxtaposition of the catalytic and substrate recognition module subunits relative to coactivators and APC-C inhibitors. 
History Note English:   2014 
Allowable Qualifiers English:  
AD administration & dosage AE adverse effects
AG agonists AN analysis
AI antagonists & inhibitors BI biosynthesis
BL blood CF cerebrospinal fluid
CS chemical synthesis CH chemistry
CL classification CT contraindications
DF deficiency DU diagnostic use
DE drug effects EC economics
GE genetics HI history
IM immunology IP isolation & purification
ME metabolism PK pharmacokinetics
PD pharmacology PH physiology
PO poisoning RE radiation effects
SE secretion ST standards
SD supply & distribution TU therapeutic use
TO toxicity UL ultrastructure
UR urine  
Record Number:   55281 
Unique Identifier:   D064195 

Occurrence in VHL:
 

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